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张克勤


教授/ kqzhang@ynu.edu.cn /微生物学

个人简历

1995.9-1998.7，中国农业大学，植物病理学专业，获博士学位；

1998.7-2001.1，565net必赢客户端，工业微生物发酵工程重点实验室，实验室主任；

2003-2015.12，565net必赢客户端，省部共建云南生物资源保护与利用国家重点实验室培育基地，实验室主任；

2015.12-至今，省部共建565net必赢客户端生物资源保护与利用国家重点实验室，实验室主任；

2001.1-至今，565net必赢客户端，副校长；

 

主要研究方向

专注于作物病原线虫生物防治研究，通过发掘杀线虫微生物新资源和新化合物、确定致病毒力因子、揭示微生物与线虫互作分子机制，开发出拥有自主知识产权的线虫生物农药并实现产品的规模化生产和应用，为解决线虫防治的难题做出了重要贡献。

 

主要论文


  1. Yang ZS, Ma LQ, Zhu K, Yan JY, Bian L, Zhang KQ*, Zou CG*. 2016.Pseudomonas toxin pyocyanin triggers autophagy: Implications for pathoadaptive mutations. Autophagy. 12: 1-14. (IF2016= 9.108)

  2. Tao J, Ma YC, Yang ZS, Zou CG*, Zhang KQ*. 2016. Octopamine connects nutrient cues to lipid metabolism upon nutrient deprivation. Science Advances. 2: e1501372-e1501372. (IF2015= NA) 

  3. Li J, Zou CG, Xu JP, Ji XL, Niu XM, Yang JK, Huang XW and Zhang KQ*. 2015. Molecular mechanisms of nematode-nematophagous microbe interactions: basis for biological control of plant-parasitic nematodes. Annual Review of Phytopathology. 53: 67-95. (IF2016=9.308) 

  4. Dai LL, Gao JX, Zou CG, Ma YC, Zhang KQ*. 2015. Unfolded Protein Response in C. elegans during Pseudomonas aeruginosa Infection. PLoS Pathogens. 11: e1004606 (IF2016=7.003)

  5. Wang X, Li GH, Zou CG, Ji XL, Liu T, Zhao PJ, Liang LM, Xu JP, An ZQ, Zheng X, Qin YK, Tian MQ, Xu YY, Ma YC, Yu ZF, Huang XW, Liu SQ, Niu XM, Yang JK, Huang Y, Zhang KQ*. 2014. Bacteria can mobilize nematode-trapping fungi to kill nematodes. Nature Communication. 16(5): 5776 (IF2016=11.329).

  6. Zou CG, Ma YC, Dai LL, Zhang KQ*. 2014. Autophagy protects C. elegans against necrosis during Pseudomonas aeruginosainfection. Proceedings of the National Academy of Sciences USA. 111: 12480-5 (IF2016=9. 432).

  7. Zou CG, Tu Q, Niu J, Ji XL, Zhang KQ*. 2013. The DAF-16/FOXO Transcription Factor Functions as a Regulator of Epidermal Innate Immunity. PLoS Pathogens 9: e1003660 (IF2016=7.003).

  8. Guo JP, Zhu CY, Zhang CP, Chu YS, Wang YL Zhang JX, Wu DK, Zhang KQ*, Niu XM*. 2012. Thermolides, potent nematocidal PKS-NRPS hybrid metabolites from thermophilic Fungus Talaromyces thermophilus. Journal of the American Chemical Society. 134:20306-20309 (IF2016=13.038).

  9. Yang J, Wang L, Ji X, Feng Y, Li X, Zou C, Xu J, Ren Y, Mi Q, Wu J, Liu Sh, Liu Y, Huang X, Wang H, Niu X, Li J, Liang L, Ji K, Zhou W, Yu Z, Li G, Liu Y, Li L, Qiao M, Feng L, Zhang KQ*. 2011. Genomic and proteomic analyses of the fungus Arthrobotrys oligospora provide insights into nematode-trap formation. PLoS Pathogens. 7:e1002179 (IF2016= 7.003).

  10. Niu Q, Huang X, Zhang L, Xu J, Yang D, Wei K, Niu X, An Z, Bennett JW, Zou C, Yang J, Zhang KQ*. 2010. A Trojan horse mechanism of bacterial pathogenesis against nematodes. Proceedings of the National Academy of Sciences USA. 107:16631–16636 (IF2016=9. 432).